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Physical Sciences Physical Pharmaceutics II Experiments

Aim

Theory

Pretest

Procedure

Simulation

Posttest

References

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Aim

Theory

Pretest

Procedure

Simulation

Posttest

References

Feedback

Determination of Bulk Density and Tapped Density of Pharmaceutical Powders Using Digital Bulk Density Apparatus

Choose difficulty:

Beginner

Intermediate

Advanced

1. The formula for Carr’s Index (CI) is:

a: (Tapped Density / Bulk Density) × 100 Explanation

Explanation

b: (Bulk Density / Tapped Density) × 100 Explanation

Explanation

c: [(Tapped Density – Bulk Density) / Tapped Density] × 100 Explanation

Explanation

d: [(Bulk Density – Tapped Density) / Bulk Density] × 100 Explanation

Explanation

2. If Hausner Ratio > 1.25, it indicates:

a: Poor flowability of the powder Explanation

Explanation

b: Excellent flowability Explanation

Explanation

c: Uniform particle size Explanation

Explanation

d: Low compressibility Explanation

Explanation

3. When the difference between two consecutive tapped volumes is less than 2%:

a: Tapping should continue Explanation

Explanation

b: Tapping can be stopped as constant volume is achieved Explanation

Explanation

c: Sample should be replaced Explanation

Explanation

d: Cylinder should be refilled Explanation

Explanation

4. A powder has a bulk density of 0.5 g/mL and tapped density of 0.65 g/mL. Its Hausner Ratio is:

a: 1.15 Explanation

Explanation

b: 1.30 Explanation

Explanation

c: 0.77 Explanation

Explanation

d: 1.50 Explanation

Explanation

5. One of the major factors affecting bulk and tapped density results is:

a: Color of the powder Explanation

Explanation

b: Particle size and shape Explanation

Explanation

c: Odor of the powder Explanation

Explanation

d: Storage container material Explanation

Explanation

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